關節炎和類風濕性關節炎

\r\nRheumatoid arthritis (RA)—the inflammatory “flaring” arthritis—is a systemic autoimmune disease. Approximately 165,000 new cases are diagnosed annually in the United States.⁵ All parts of the body can be affected, including the heart and lungs, but RA is often characterized by symmetrical finger and wrist pain. One of the most potentially devastating forms of arthritis, it typically appears in the third and fourth decades of life and affects women more frequently than men.

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Quest offers a full suite of testing for RA, including a test for the 14-3-3η protein biomarker.

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Rheumatoid arthritis tests:
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類風濕性關節炎（RA） - 炎症“耀斑”關節炎 - 是一種全身自身免疫疾病。在美國每年診斷約165,000例新案件。^5.身體的所有部位都可以受到影響，包括心髒和肺，但是Ra通常是對稱的手指和手腕疼痛的特征。最潛在毀滅性的關節炎形式之一，它通常出現在生命的第三和第四十年中，並影響女性比男性更頻繁。

任務為RA提供全套測試，包括對14-3-3蛋白生物標誌物的測試。

類風濕性關節炎測試：

*Panel components may be ordered separately.

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*麵板組件可以單獨訂購。

\r\nKnown as the “wear and tear” arthritis, osteoarthritis (OA) is the most common form of arthritis, affecting over 30 million Americans.⁶

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Many symptoms of OA and RA overlap, including pain, swelling, and stiffness in the joints. These similarities can cause difficulty when differentiating the diseases. Differential diagnosis of OA and RA is important because treatments differ.⁷

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Depending on the joint, classification criteria may include joint symptoms (pain, stiffness, swelling, enlargement, deformation), age, erythrocyte sedimentation rate, radiologic findings (presence of osteophytes or narrowing of joint space), synovial fluid tests (color, appearance, white blood cell count), and the sensation of crackling in the joint (crepitus).⁸

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In addition, some laboratory markers are elevated in RA patients but normal in OA patients. A positive or elevated result for rheumatoid factor, cyclic citrullinated peptide antibody, or the 14-3-3η protein may suggest inflammatory arthritis, such as RA, rather than OA.

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Osteoarthritis tests:

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被稱為“磨損撕裂”關節炎，骨關節炎（OA）是最常見的關節炎形式，影響超過3000萬美國人。^6.

OA和RA重疊的許多症狀，包括關節中的疼痛，腫脹和僵硬。這些相似之處會導致疾病的困難造成困難。OA和RA的差異診斷很重要，因為治療有所不同。^7.

根據關節，分類標準可包括關節症狀（疼痛，剛度，腫脹，擴大，變形），年齡，紅細胞沉降率，放射學結果（關節空間的骨折或縮小），滑膜液測試（顏色，外觀，外觀，白細胞計數，以及關節（縐紗）裂紋的感覺。^8.

此外，一些實驗室標記物在RA患者中升高，但在OA患者中正常。類風濕因子，環狀瓜氨酸肽抗體或14-3-3蛋白的陽性或升高的結果可以提示炎症性關節炎，例如Ra，而不是OA。

骨關節炎測試：